Exploring DNA Damage Responses in Cancer Therapy: Mechanisms, Strategies, and Future Directions

Authors

  • R. Amulya Research Scholar, Department of Pharmacy Practice, Geethanjali College of Pharmacy. Author
  • N. Sravani Research Scholar, Department of Pharmacy Practice, Geethanjali College of Pharmacy. Author
  • B. Sai Sree Reddy Research Scholar, Department of Pharmacy Practice, Geethanjali College of Pharmacy. Author
  • Dr. Abdul Nazer Ali Department of Pharmacy Practice, Geethanjali College of Pharmacy Author

Keywords:

DNA damage, Repair, Cancer therapy, Mechanisms, Strategies.

Abstract

DNA disruption is a pivotal event in carcinogenesis, emanating from intrinsic cellular processes and external environmental agents. When inadequately repaired, it leads to hereditary perturbation and oncogenic transformation. This review presents an extensive outline of the molecular mechanisms underlying DNA impairment and repair, focusing on their application in cancer therapy.

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Published

2025-05-30

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Section

Articles